I respectfully suggest that the first step is that we need the good doctor to generate a fistful of those systems that he generates and select one system.
He should post the details of that system as a new topic.
This becomes the start of that place.
Then let's collectively fill in the details of this system, world by world and moon by moon, with a goal towards creating a backdrop of Places to Go and Things to Do into which a referee can insert some of those Patrons and Adventures.
That's basically what the System Books I did for Spica were
You can always pick a few out of the ones I made on the Ultra-realistic worldbuilding thread
to start from if you want.
Yeah, those are great.
The only 'problem' (I wish that I had more of those problems) is that they already come with the 'adventure' built in. I was thinking more along the lines of just some background scenery that a referee could use to replace a generic 'medium world, tainted atmosphere, stuck in the Starport' to create a more interesting PLACE where the characters can run into whatever PATRON and mission that the Referee was planning on using anyway.
I think that those might be the perfect place to look for a start.
Where I would like to kick the tires on some new ideas are describing things from the observer's perspective a little more. For example, from the main world, is the sun a tiny bright dot or a giant red globe filling half of the sky? If there are plants, what color are they? If there are animals, what Earth Family do they most resemble? How about a complete ecosystem ... what eats what?
Is there regular shuttle service to other parts of the system?
What about that orbital refinery at the gas giant that is an independent colony with a population in the thousands and a source of second hand parts for starships (and an old starship boneyard).
Perhaps one of the moons houses an artist colony of about a hundred free spirits. Rumored to have one of the finest restaurants in the system. Some say the food alone is worth the trip out there.
Just background ... Places to go and stuff to do ... Waiting for a Referee to come along and supply the adventure. There are all these 'adventure ideas' published in all sorts of books, but you never have any ready made placed to actually have an adventure. THAT is what I would like to try and fix.